Polyetheretherketone (PEEK) implant abutments are widely used in implant dentistry; however, they do not protect the implant against infections. We demonstrated that graphene oxide (GO) coating enhances the integration between implant surfaces and gingival tissues, which is crucial for peri-implant health. The GO coating was tightly fixed onto the PEEK surface by doping with dopamine which is self-polymerized into poly-dopamine (PDA). The in vitro study included antimicrobial and cellular tests. It revealed the inhibition of bacteria like Porphyromonas gingivalis (P. gingivalis), Fusobacterium nucleatum (F. nucleatum), and Streptococcus mutans (S. mutans). Moreover, it exhibited good adhesion and proliferation of human gingival fibroblasts (HGFs). Our results revealed that the PEEK-PDA-GO coating resisted bacteria and protected soft tissues against peri-implant complications.

聚醚醚酮（PEEK）种植体基台被广泛用于种植体牙科领域。但是，它们不能保护植入物免受感染。我们证明了氧化石墨烯（GO）涂层增强了植入物表面和牙龈组织之间的整合，这对于植入物周围的健康至关重要。通过掺入多巴胺将GO涂层牢固地固定在PEEK表面上，该多巴胺会自动聚合成聚多巴胺（PDA）。在体外研究中包含了抗微生物和细胞试验。它显示出对牙龈卟啉单胞菌（P. gingivalis），核纤梭菌（F. nucleatum）和变形链球菌（S. mutans）等细菌的抑制作用。）。此外，它表现出良好的粘附力和人牙龈成纤维细胞（HGFs）的增殖。我们的结果表明，PEEK-PDA-GO涂层可抵抗细菌并保护软组织免受植入物周围并发症的影响。