Journal of Psychosomatic Research ( IF 3.5 ) Pub Date : 2021-05-25 , DOI: 10.1016/j.jpsychores.2021.110534 Sun Mi Kim 1 , Doug Hyun Han 1
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Objective
We aimed to identify differences in brain functional connectivity (FC) and characteristics of body sensation between sports players and patients with somatic symptom disorder (SSD), in order to investigate the neurobiological basis of SSD.
Methods
Thirty-five sports players (SPORTS group), 36 patients with SSD (SOM group), and 33 healthy control participants (HC group) underwent resting-state functional magnetic resonance imaging. We used a seed-based FC analysis.
Results
Both groups showed increased brain activity in the left precuneus. The level of body intelligence in the SPORTS group and the level of somatosensory amplification in the SOM group were positively correlated with brain activity in the left precuneus. The SPORTS group showed increased FC between the left precuneus and the right/left insula compared to the HC group. The SOM group showed increased FC between the left precuneus and the right parahippocampal gyrus compared to the HC group. The SPORTS group showed increased FC between the left precuneus and left posterior cingulate gyrus compared to the SOM group.
Conclusion
Increased FC between the precuneus within the default mode network (DMN) and the insula connected to the sensorimotor network in sports players may be related to better somatosensory functions. In contrast, increased FC between the precuneus of the DMN and the parahippocampal gyrus of the affective network in SSD may be associated with dysfunctional processing and misconception of information. Future studies should examine whether treatments for improving affective processing normalize the affective network, and if this is correlated with somatic symptom improvement.
中文翻译：
运动员与躯体症状障碍患者感觉运动网络内大脑活动的比较
客观的
我们旨在确定运动员和躯体症状障碍 (SSD) 患者在大脑功能连接 (FC) 和身体感觉特征方面的差异，以研究 SSD 的神经生物学基础。
方法
35 名运动员（SPORTS 组）、36 名 SSD 患者（SOM 组）和 33 名健康对照组（HC 组）接受了静息态功能磁共振成像。我们使用了基于种子的 FC 分析。
结果
两组都显示出左侧楔前叶的大脑活动增加。SPORTS组的身体智力水平和SOM组的体感放大水平与左楔前叶的大脑活动呈正相关。与 HC 组相比，SPORTS 组显示左楔前叶和右/左岛叶之间的 FC 增加。与 HC 组相比，SOM 组显示左侧楔前叶和右侧海马旁回之间的 FC 增加。与 SOM 组相比，SPORTS 组显示左侧楔前叶和左侧后扣带回之间的 FC 增加。
结论
默认模式网络 (DMN) 内的楔前叶和连接到运动运动员感觉运动网络的岛叶之间的 FC 增加可能与更好的体感功能有关。相比之下，在 SSD 中 DMN 的楔前叶和情感网络的海马旁回之间的 FC 增加可能与信息处理功能障碍和误解有关。未来的研究应该检查改善情感处理的治疗是否使情感网络正常化，以及这是否与躯体症状的改善相关。
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