Neurodegeneration of the substantia nigra in Lewy body disease is associated with iron deposition, which increases the magnetic susceptibility of the substantia nigra on MRI. Our objective was to measure iron deposition in the substantia nigra in patients with probable dementia with Lewy bodies (pDLB) and patients who are at risk for pDLB by quantitative susceptibility mapping (QSM).

中文翻译：

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黑质的 MRI 定量磁化率图作为路易体病的早期生物标志物

路易体病中黑质的神经变性与铁沉积有关，铁沉积会增加 MRI 上黑质的磁化率。我们的目的是通过定量磁敏图 (QSM) 测量可能患有路易体痴呆 (pDLB) 的患者和有患 pDLB 风险的患者黑质中的铁沉积。