Biodegradable polyester nanomaterials-based drug delivery vehicles (DDVs) have been largely used in most of the cancer treatments due to its high biological performance and wider applications. In several previous studies, various biodegradable and biocompatible polyester backbones were used which are poly(lactic acid) (PLA), poly(ε-caprolactone) (PCL), poly(propylene fumarate) (PPF), poly(lactic-co-glycolic acid) (PLGA), poly(propylene carbonate) (PPC), polyhydroxyalkanoates (PHA), and poly(butylene succinate) (PBS). These polyesters were fabricated into therapeutic nanoparticles that carry drug molecules to the target site during the cancer disease treatment. In this review, we elaborately discussed the chemical synthesis of different synthetic polyesters and their use as nanodrug carriers (NCs) in cancer treatment. Further, we highlighted in brief the recent developments of metal-free semi-aromatic polyester nanomaterials along with its role as cancer drug delivery vehicles.

基于生物可降解聚酯纳米材料的药物传递载体（DDV）由于其高生物学性能和广泛应用而已广泛用于大多数癌症治疗中。在以前的一些研究中，使用了各种可生物降解和生物相容性的聚酯主链，包括聚乳酸（PLA），聚ε-己内酯（PCL），聚富马酸丙二酯（PPF），聚乳酸-乙醇酸共聚物酸（PLGA），聚碳酸亚丙酯（PPC），聚羟基链烷酸酯（PHA）和聚丁二酸丁二酯（PBS）。这些聚酯被制成治疗性纳米颗粒，在癌症疾病治疗期间将药物分子携带到目标部位。在这篇综述中，我们详细讨论了不同合成聚酯的化学合成及其在癌症治疗中作为纳米药物载体（NCs）的用途。更多，