Evidence for a biparental mode of mitochondrial DNA (mtDNA) inheritance has been sparse and remains controversial. Recent studies using a range of complementary techniques do not support paternal transmission of mtDNA and highlight the co-amplification of rare, concatenated nuclear mtDNA segments as a technical artefact that may explain previous observations. This Comment discusses recent studies supporting the existence of concatenated mitochondrial DNA (mtDNA) segments integrated into the nuclear genome, which may explain previous observations suggesting the existence of a biparental mode of mtDNA inheritance.

中文翻译：

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重新审视线粒体 DNA 的双亲遗传

线粒体 DNA (mtDNA) 遗传的双亲模式的证据很少，并且仍有争议。最近使用一系列互补技术的研究不支持 mtDNA 的父系传递，并强调罕见的串联核 mtDNA 片段的共同扩增是一种技术人工制品，可以解释以前的观察结果。这篇评论讨论了最近的研究，支持整合到核基因组中的串联线粒体 DNA (mtDNA) 片段的存在，这可能解释了先前的观察表明存在双亲模式的 mtDNA 遗传。