The metabolomics analysis was used in this study to examine the changes in metabolite profile of Moldavian balm under water-deficit stress, symbiosis with arbuscular mycorrhizal fungus, plant growth-promoting rhizobacteria, and their interactions. This project was realized by applying a completely randomized model considering three factors, the arbuscular mycorrhizal fungus Claroideoglomus etunicatum, the rhizobacteria Micrococcus yunnanensis, and irrigation regimes (100, 70, and 40% field capacity). The results showed that the sugar metabolisms are the most affected metabolic pathways under drought stress. Moreover, the increase of some amino acids, citric acid cycle intermediates, and phenolic acid metabolites could contribute to the tolerance mechanisms of non-inoculated plants against water-deficit stress. These results suggested that soil microorganisms could be used to mitigate the negative impacts of drought stress by inducing the accumulation of some of the intermediary metabolites that act as osmolytes or their precursors. Overall, these results indicated that symbiotic association with soil microorganisms leads to metabolic and physiological adaptation which can increase the performance of this important medicinal plant under drought conditions.

代谢组学分析用于研究缺水胁迫，与丛枝菌根真菌共生，促进植物生长的根瘤菌及其相互作用下摩尔达维亚香脂的代谢产物谱变化。该项目是通过应用考虑三个因素的完全随机模型来实现的，这三个因素是：丛枝菌根真菌Claroideoglomus etunicatum，根瘤菌云南微球菌（Micrococcus yunnanensis），灌溉制度（田间灌溉能力分别为100％，70％和40％）。结果表明，糖代谢是干旱胁迫下影响最大的代谢途径。此外，某些氨基酸，柠檬酸循环中间体和酚酸代谢产物的增加可能有助于未接种植物抵御缺水胁迫的机制。这些结果表明，土壤微生物可通过诱导某些充当渗透压或其前体的中间代谢产物的积累来减轻干旱胁迫的负面影响。总体而言，这些结果表明与土壤微生物的共生关系导致代谢和生理适应，这可以提高这种重要药用植物在干旱条件下的性能。