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Molecular Mechanisms of miR-1271 Dysregulation in Human Cancer
DNA and Cell Biology ( IF 2.6 ) Pub Date : 2021-06-08 , DOI: 10.1089/dna.2021.0100
Kena Zhou 1 , Congbo Cai 2 , Mengsha Zou 3 , Yi He 1 , Shiwei Duan 3
Affiliation  

MicroRNA is a small noncoding RNA that plays a role in regulating gene expression. miR-1271 is a tumor suppressor microRNA, which is related to the biological changes of many cancers. miR-1271 is considered a biomarker with a potential prognosis and high therapeutic value in tumors. Besides, the expression of miR-1271 is also regulated by many factors. In this study, we summarize the role of miR-1271 in tumors, focusing on the molecular mechanisms of the target genes of miR-1271. Our review will provide a comprehensive understanding of miR-1271 in tumors, as well as ideas for subsequent tumor research related to miR-1271.

中文翻译:

miR-1271在人类癌症中失调的分子机制

MicroRNA 是一种小的非编码 RNA,在调节基因表达中发挥作用。miR-1271是一种抑癌微RNA,与多种癌症的生物学变化有关。miR-1271被认为是一种在肿瘤中具有潜在预后和高治疗价值的生物标志物。此外,miR-1271的表达也受多种因素的调控。本研究总结了miR-1271在肿瘤中的作用,重点探讨了miR-1271靶基因的分子机制。我们的综述将提供对肿瘤中 miR-1271 的全面了解,以及后续与 miR-1271 相关的肿瘤研究的思路。
更新日期:2021-06-09
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