Excessive sedentariness has been related to poorer cognitive control in adults. Sedentariness may compound obesity-related impairments in response inhibition, but its relationship to response inhibition remains poorly understood. This study investigated the relationship between accelerometer-measured sedentary time (ST, min/day), performance on the Oddball and NoGo tasks, N2 and P3-ERP indices of response inhibition and attentional control in 80 adults with overweight and obesity (55 females, M_age = 35.2 ± 5.8 years, BMI = 32.8 ± 5.3 kg/m²). ST was not related to performance on the Oddball task. However, more sedentary adults had larger P3b amplitude to targets. Higher ST was also related to increased attentional resource allocation during NoGo target and nontarget trials as indicated by higher P3b amplitudes across centroparietal sites (C1, Cz, C2, CP1, CPz, CP2; ps ≤ .03). ST was negatively indirectly related to target accuracy on NoGo trials through its association with faster response times to nontargets (95% percentile bootstrap CI for a standardized effect: −0.182, −0.014). ST was not related to N2 amplitude on either Oddball or NoGo target trials. Adjustment for moderate-to-vigorous physical activity (MVPA; all models), age (models with P3b NoGo target amplitude, N2 NoGo target amplitude and latency), and % fat mass (models with target NoGo accuracy and N2 NoGo target amplitude) did not modulate behavioral findings. MVPA did not significantly predict P3b amplitude. Our results suggest suboptimal response inhibition due to trading accuracy for speed and despite the upregulation of attentional resources among more sedentary adults with overweight and obesity.

中文翻译：

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久坐时间与超重和肥胖成人的反应抑制缺陷有关：加速度计和事件相关脑电位研究

过度久坐与成人较差的认知控制有关。久坐可能会在反应抑制中复合肥胖相关的损害，但它与反应抑制的关系仍然知之甚少。本研究调查了 80 名超重和肥胖成人（55 名女性、55 名女性、M_年龄 = 35.2 ± 5.8 岁，BMI = 32.8 ± 5.3 kg/m ²）。ST 与 Oddball 任务的表现无关。然而，久坐不动的成年人对目标的 P3b 幅度更大。较高的 ST 还与 NoGo 目标和非目标试验期间注意力资源分配的增加有关，如中央顶叶较高的 P3b 振幅所示（C1、Cz、C2、CP1、CPz、CP2；p s ≤ .03）。ST与目标准确度负间接相关在 NoGo 试验中，它与对非目标的更快响应时间相关联（标准化效应的 95% 百分位引导 CI：-0.182，-0.014）。在 Oddball 或 NoGo 目标试验中，ST 与 N2 幅度无关。对中等到剧烈的身体活动（MVPA；所有模型）、年龄（具有 P3b NoGo 目标幅度、N2 NoGo 目标幅度和潜伏期的模型）和脂肪量百分比（具有目标 NoGo 准确度和 N2 NoGo 目标幅度的模型）进行了调整不调节行为发现。MVPA 没有显着预测 P3b 幅度。我们的研究结果表明，由于速度的交易准确性以及注意力资源在更多久坐的超重和肥胖成年人中注意力资源的上调，反应抑制并不理想。