Major advances in delivery systems in recent years have turned radiotherapy (RT) into a more effective way to manage prostate cancer. Still, adjacency of organs at risk (OARs) can severely limit RT benefits. Rectal spacer implant in recto-prostatic space provides sufficient separation between prostate and rectum, and therefore, the opportunity for potential dose escalation to the target and reduction of OAR dose. Pretreatment simulation of spacer placement can potentially provide decision support to reduce the risks and increase the efficacy of the spacer placement procedure.

中文翻译：

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FEMOSSA：前列腺 - 直肠垫片放置的患者特定有限元模拟，前列腺癌放射治疗的预测模型

近年来，递送系统的重大进步已将放射治疗 (RT) 转变为一种更有效的前列腺癌治疗方法。尽管如此，危险器官 (OAR) 的邻接会严重限制放疗的益处。直肠前列腺空间中的直肠间隔植入物在前列腺和直肠之间提供了足够的分离，因此，有机会将潜在剂量增加到目标和减少 OAR 剂量。垫片放置的预处理模拟可以潜在地提供决策支持，以降低风险并提高垫片放置程序的功效。