Aims

This study aimed to compare three approaches of blood glucose monitoring (BGM) frequency attainment and to examine their associations with glycemic control in youth with type 1 diabetes (T1D).

Methods

Cross-sectional data was derived from the baseline assessment in three clinical trials. Clinical and demographic characteristics of youth with T1D was obtained by chart review. BGM frequency was assessed by parent-youth interview, chart review, and meter downloads. To examine the relationship between A1c and frequency of BGM we performed analysis of variance.

Results

In youth with T1D (N = 385, 50% female, age 13.6 ± 2.5 years, 74% pump users), the 3 methods of assessing BGM frequency were significantly correlated. Frequency by self-report (6.4 ± 2.3 times/day) was significantly higher than both meter download (5.6 ± 2.4 times/day, p < 0.0001) and clinician report (5.7 ± 2.4 times/day, p < 0.0001). For all methods, more frequent BGM was associated with lower A1c and lower mean glucose (p < 0.0001). For each additional daily blood glucose check, there was a 0.2% decrease in A1c (p < 0.0001).

Conclusion

BGM remains a potent predictor of glycemic control, warranting continued targeting in clinical efforts to improve glycemic management in youth with T1D.

中文翻译：

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血糖监测 (BGM) 对许多人来说仍然很重要：BGM 频率与青少年 1 型糖尿病患者血糖控制的关联

目标

本研究旨在比较三种血糖监测 (BGM) 频率达到的方法，并检查它们与青少年 1 型糖尿病 (T1D) 血糖控制的关系。

方法

横断面数据来自三项临床试验的基线评估。通过图表审查获得了青少年 T1D 的临床和人口统计学特征。BGM 频率通过家长与青少年的访谈、图表审查和仪表下载来评估。为了检查 A1c 和 BGM 频率之间的关系，我们进行了方差分析。

结果

在患有 T1D 的青年（N = 385，50% 女性，年龄 13.6 ± 2.5 岁，74% 泵使用者）中，评估 BGM 频率的 3 种方法显着相关。自我报告的频率（6.4 ± 2.3 次/天）显着高于仪表下载（5.6 ± 2.4 次/天，p < 0.0001）和临床医生报告（5.7 ± 2.4 次/天，p < 0.0001）。对于所有方法，更频繁的 BGM 与更低的 A1c 和更低的平均葡萄糖相关（p < 0.0001）。每增加一次每日血糖检查，A1c 就会降低 0.2%（p < 0.0001）。

结论

BGM 仍然是血糖控制的有效预测因子，需要在临床工作中继续瞄准以改善 T1D 青年的血糖管理。