Recombinant thrombomodulin (rhTM) is potentially effective in the treatment of disseminated intravascular coagulation (DIC). Several studies related to drugs for the treatment of acute cholangitis have shown negative results in improvement of overall survival (OS) with rhTM. The aim of this multicenter study was to evaluate the clinical effectiveness of rhTM in patients with acute cholangitis and sepsis-induced DIC who underwent biliary drainage.

中文翻译：

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重组凝血调节蛋白给药对严重急性胆管炎引起的弥散性血管内凝血的临床影响（Recover-AC 研究）

重组血栓调节蛋白 (rhTM) 可有效治疗弥散性血管内凝血 (DIC)。几项与治疗急性胆管炎药物相关的研究表明，rhTM 在改善总生存期 (OS) 方面取得了负面结果。这项多中心研究的目的是评估 rhTM 在接受胆道引流的急性胆管炎和脓毒症诱发的 DIC 患者中的临床疗效。