Surface plasmon resonance imaging biosensors have a number of advantages that make them superior to other analytical methods. These include the possibility of label-free detection, speed and high sensitivity to low protein concentrations. The aim of this study was to create and analyze biochips, with the help of which it is possible to test cystatin C in patient urine samples and compare the results with the one-time traditional ELISA method. The main advantage of the surface plasmon resonance imaging method is the possibility of repeated measurements over a long period of time in accordance with clinical practice. The surface of the biochip was spotted with anticystatin C and a negative control of mouse IgG at a ratio of 1:1. The aforementioned biochip was first verified using standard tests and then with patient samples, which clearly confirmed the required sensitivity even for very low concentrations of cystatin C.

中文翻译：

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表面等离子共振法测定生物样品中胱抑素C。

表面等离子体共振成像生物传感器具有许多优势，使其优于其他分析方法。这些包括无标记检测的可能性、速度和对低蛋白质浓度的高灵敏度。这项研究的目的是创建和分析生物芯片，借助该芯片可以测试患者尿液样本中的胱抑素 C，并将结果与​​一次性传统 ELISA 方法进行比较。表面等离子体共振成像方法的主要优点是可以根据临床实践在很长一段时间内重复测量。在生物芯片的表面以 1:1 的比例用抗胱抑素 C 和小鼠 IgG 的阴性对照点样。上述生物芯片首先使用标准测试进行验证，然后使用患者样本进行验证，