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Cisplatin Activates the Growth Inhibitory Signaling Pathways by Enhancing the Production of Reactive Oxygen Species in Non-small Cell Lung Cancer Carrying an EGFR Exon 19 Deletion.
Cancer Genomics & Proteomics ( IF 2.6 ) Pub Date : 2021-5-18 , DOI: 10.21873/cgp.20273
Md Mohiuddin 1 , Kazuo Kasahara 2
Affiliation  

Cisplatin is a potent anticancer drug for treating several types of cancer, including non-small-cell lung cancer (NSCLC). In this study, we investigated the cytotoxicity and mechanism of action of cisplatin in the human NSCLC cell line PC9.

中文翻译:

顺铂通过增强携带 EGFR 外显子 19 缺失的非小细胞肺癌中活性氧的产生来激活生长抑制信号通路。

顺铂是一种有效的抗癌药物,可用于治疗多种类型的癌症,包括非小细胞肺癌 (NSCLC)。在这项研究中,我们研究了顺铂在人 NSCLC 细胞系 PC9 中的细胞毒性和作用机制。
更新日期:2021-05-20
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