The safe use of nuclear energy has always been one of the vital factors hindering the development of nuclear energy. Especially after the Chernobyl Disaster in 1986 and the Fukushima nuclear power plant accident in 2011, the attitude of the government and the public towards the safe handling of nuclear power has become increasingly negative. International discussions on the emergency decision of nuclear accidents have never ceased, and the process of dealing with the accidents’ aftermath is still difficult. Therefore, it is worth researching on the trend, effectiveness and perfection of the nuclear emergency response strategies issued by the government. This article selected the Asia-Pacific region as the research object, deeply reviewed the optimization policy and management of Australia, China, Thailand, Russia and other countries since 1953. With the constantly innovation of nuclear technology, this work is of great significance to formulate relevant policies and to improve the global nuclear emergency response strategies in the future.