Objective

Menopause is a normal physiological process experienced by women, but it is often accompanied by physical and emotional symptoms that may negatively affect quality of life. This meta-analysis aimed to evaluate the effectiveness of mindfulness-based interventions on quality of life and menopausal symptoms by examining randomized controlled trials.

Methods

A systematic search was conducted across six electronic databases to collect relevant articles published up to June 30, 2020. The articles' quality was assessed using the modified Jadad scale. We performed a meta-analysis with Review Manager 5.3, calculating 95% confidence intervals and standardized mean differences, and conducted sensitivity analyses.

Results

The meta-analysis of five randomized controlled trials included 475 participants. The results indicated that the mindfulness-based intervention groups showed significant improvements in total quality of life and vasomotor and physical quality of life, compared to control groups (standardized mean differences range: from −0.48 to −0.68, all ps < 0.05). After the sensitivity analyses, evidence of heterogeneity remained. Insufficient data prevented conducting a meta-analysis with the sexual subscale of MENQOL or on vasomotor symptoms of menopause.

Conclusion

For menopausal women, mindfulness-based interventions may improve quality of life (except for psychological and sexual subscales). However, there is insufficient evidence to analyze whether such interventions can reduce vasomotor-related menopausal symptoms. Although heterogeneity should be carefully assessed, mindfulness-based interventions may be a novel approach for improving women's overall quality of life during menopause. However, further research is needed to verify these effects.

中文翻译：

---

基于正念的干预对更年期妇女生活质量和更年期症状的有效性：荟萃分析

客观的

更年期是女性所经历的正常生理过程，但它往往伴随着可能对生活质量产生负面影响的身体和情绪症状。这项荟萃分析旨在通过检查随机对照试验来评估基于正念的干预措施对生活质量和更年期症状的有效性。

方法

在六个电子数据库中进行了系统搜索，以收集截至 2020 年 6 月 30 日发表的相关文章。使用修改后的 Jadad 量表评估文章的质量。我们使用 Review Manager 5.3 进行了荟萃分析，计算了 95% 置信区间和标准化平均差，并进行了敏感性分析。

结果

五项随机对照试验的荟萃分析包括 475 名参与者。结果表明，与对照组相比，基于正念的干预组在总体生活质量、血管舒缩和身体生活质量方面显示出显着改善（标准化平均差异范围：-0.48 至 -0.68，所有 ps < 0.05）。在敏感性分析之后，异质性的证据仍然存在。由于数据不足，无法对 MENQOL 的性分量表或更年期血管舒缩症状进行荟萃分析。

结论

对于更年期女性，基于正念的干预可能会提高生活质量（心理和性分量表除外）。然而，没有足够的证据来分析此类干预措施是否可以减少血管舒缩相关的更年期症状。尽管应仔细评估异质性，但基于正念的干预可能是改善更年期女性整体生活质量的一种新方法。然而，需要进一步的研究来验证这些影响。