Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors,Clinical & Translational Immunology

当前位置： X-MOL 学术 › Clin. Transl. Immunol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors
Clinical & Translational Immunology ( IF 4.6 ) Pub Date : 2021-05-16 , DOI: 10.1002/cti2.1285
Maurice Steenhuis _{1,

2} , Gerard van Mierlo _{1,

2} , Ninotska Il Derksen _{1,

2} , Pleuni Ooijevaar-de Heer _{1,

2} , Simone Kruithof _{1,

2} , Floris L Loeff _{1,

2} , Lea C Berkhout _{1,

2} , Federica Linty ₃ , Chantal Reusken ₄ , Johan Reimerink ₄ , Boris Hogema ₅ , Hans Zaaijer ₆ , Leo van de Watering ₇ , Francis Swaneveld ₈ , Marit J van Gils ₉ , Berend Jan Bosch ₁₀ , S Marieke van Ham _{1,

2} , Anja Ten Brinke _{1,

2} , Gestur Vidarsson ₃ , Ellen C van der Schoot ₃ , Theo Rispens _{1,

2}

Affiliation

Department of Immunopathology Sanquin Research Amsterdam The Netherlands.
Landsteiner Laboratory Amsterdam University Medical Centre University of Amsterdam Amsterdam The Netherlands.
Department of Experimental Immunohematology Sanquin Research and Landsteiner Laboratory Amsterdam University Medical Centre Amsterdam The Netherlands.
Department of Infectious Diseases Public Health Service region Utrecht Utrecht The Netherlands.
Department of Virology Sanquin Diagnostic Services Amsterdam The Netherlands.
Sanquin Blood Supply Foundation and Amsterdam University Medical Centre Amsterdam The Netherlands.
Sanquin Blood Bank Unit Transfusion Medicine Leiden The Netherlands.
Department of Transfusion Medicine Sanquin Blood Bank Amsterdam The Netherlands.
Department of Medical Microbiology Amsterdam UMC University of Amsterdam Amsterdam The Netherlands.
Virology Division Department of Infectious Diseases and Immunology Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands.

Characterisation of the human antibody response to SARS‐CoV‐2 infection is vital for serosurveillance purposes and for treatment options such as transfusion with convalescent plasma or immunoglobulin products derived from convalescent plasma. In this study, we longitudinally and quantitatively analysed antibody responses in RT‐PCR‐positive SARS‐CoV‐2 convalescent adults during the first 250 days after onset of symptoms.

中文翻译：

恢复期血浆捐献者中 SARS-CoV-2 抗体的动态

人类抗体对 SARS-CoV-2 感染反应的表征对于血清监测目的和治疗选择（例如输注恢复期血浆或源自恢复期血浆的免疫球蛋白产品）至关重要。在这项研究中，我们纵向定量分析了 RT-PCR 阳性 SARS-CoV-2 恢复期成人在症状出现后 250 天内的抗体反应。

更新日期：2021-05-17

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文