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Ipsilateral access portal venous embolization (PVE) for preoperative hypertrophy exhibits low complication rates in Clavien-Dindo and CIRSE scales
CVIR Endovascular ( IF 1.2 ) Pub Date : 2021-05-17 , DOI: 10.1186/s42155-021-00227-5
Roland Brüning , Martin Schneider , Michel Tiede , Peter Wohlmuth , Gregor Stavrou , Thomas von Hahn , Andrea Ehrenfeld , Tim Reese , Georgios Makridis , Axel Stang , Karl J. Oldhafer

Portal venous embolization (PVE) is a minimal invasive preoperative strategy that aims to increase future liver remnant (FLR) in order to facilitate extended hemihepatectomy. We analyzed our data retrospectively regarding complications and degree of hypertrophy (DH). Methods: 88 patients received PVE either by particles / coils (n = 77) or by glue / oil (n = 11), supported by 7 right hepatic vein embolizations (HVE) by coils or occluders. All complications were categorized by the Clavien- Dindo (CD) and the CIRSE classification. In 88 patients (median age 68 years) there was one intervention with a biliary leak and subsequent drainage (complication grade 3 CD, CIRSE 3), two with prolonged hospital stay (grade 2 CD, grade 3 CIRSE) and 13 complications grade 1 CD, but no complications of grade 4 or higher neither in Clavien- Dindo nor in CIRSE classification. The median relative increase in FLR was 47% (SD 35%). The mean pre-intervention standardized FLR rose from 23% (SD 10%) to a post-intervention standardized FLR of 32% (SD 12%). The degree of hypertrophy (DH) was 9,3% (SD 5,2%) and the kinetic growth rate (KGR) per week was 2,06 (SD 1,84). PVE and, if necessary, additional sequential HVE were safe procedures with a low rate of complications and facilitated sufficient preoperative hypertrophy of the future liver remnant.

中文翻译:

术前肥大的同侧进入门静脉栓塞术(PVE)在Clavien-Dindo和CIRSE量表中显示出较低的并发症发生率

门静脉栓塞术(PVE)是一种微创术前策略,旨在增加将来的肝残余(FLR)以便于扩大半肝切除术。我们回顾性分析了有关并发症和肥大程度(DH)的数据。方法:88例患者通过颗粒/线圈(n = 77)或胶水/油(n = 11)接受了PVE,并由7个右肝静脉栓塞(HVE)通过线圈或封堵器进行了支持。所有并发症均按Clavien-Dindo(CD)和CIRSE分类进行分类。在88例患者(中位年龄68岁)中,有1例因胆漏和随后引流而进行的干预(并发症3级CD,CIRSE 3级),2例住院时间延长(2 CD级,CIRSE 3级),13例1级并发症,但是在Clavien-Dindo和CIRSE分类中都没有4级或更高级别的并发症。FLR的中位数相对增加为47%(标准差35%)。干预前的平均FLR从23%(标准差10%)上升到干预后的标准FLR为32%(标准差12%)。肥大程度(DH)为9.3%(标准差5,2%),每周动力学增长率(KGR)为2,06(标准差1,84)。PVE和必要时进行额外的连续HVE是安全的方法,并发症发生率低,并有助于将来肝残余的足够的术前肥大。06(SD 1,84)。PVE和必要时进行额外的连续HVE是安全的方法,并发症发生率低,并有助于将来肝残余的足够的术前肥大。06(SD 1,84)。PVE和必要时进行额外的连续HVE是安全的方法,并发症发生率低,并有助于将来肝残余的足够的术前肥大。
更新日期:2021-05-17
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