ABSTRACT

This study aims to evaluate the occurrence of food allergy to peanuts in atopic dermatitis (AD) patients and to analyse the sensitization to molecular components. The complete dermatological and allergological examination including the examination of the sensitization to molecular components with Multiplex ISAC testing was performed. Altogether 100 AD patients were examined – 48 men, 52 women, the average age 40.9 years. The food allergy to peanuts was confirmed in 27% patients; the majority of these patients are sensitized to PR 10 proteins (Ara h 8) and the minority to species-specific storage proteins and to non-specific lipid transfer protein (Ara h 9). In patients suffering from a clinical reaction to peanuts, the significant relation was confirmed to the sensitization to molecular components Aln g 1, Bet v 1, to molecular components of Timothy Phl p 1, 2, 4, 5, 6, 7 and to Mer a 1.

摘要

这项研究旨在评估特应性皮炎（AD）患者对花生食物过敏的发生，并分析其对分子成分的敏感性。进行了完整的皮肤病学和变应性检查，包括使用Multiplex ISAC测试检查对分子成分的敏感性。共检查了100位AD患者-48位男性，52位女性，平均年龄40.9岁。在27％的患者中证实了对花生的食物过敏；这些患者中的大多数对PR 10蛋白（Ara h 9）敏感，而少​​数对种特异性存储蛋白和非特异性脂质转移蛋白（Ara h 9）敏感。在对花生产生临床反应的患者中，证实了对分子成分Aln g 1，Bet v 1致敏性的显着关系。