The practice of deploying and teaching retrosynthesis is on the cusp of considerable change, which in turn forces practitioners and educators to contemplate whether this impending change will advance or erode the efficiency and elegance of organic synthesis in the future. A short treatise is presented herein that covers the concept of retrosynthesis, along with exemplified methods and theories, and an attempt to comprehend the impact of artificial intelligence in an era when freely and commercially available retrosynthetic and forward synthesis planning programs are increasingly prevalent. Will the computer ever compete with human retrosynthetic design and the art of organic synthesis?

部署和教授逆向合成的实践正处于重大变革的风口浪尖上，这反过来又迫使从业者和教育者思考这种迫在眉睫的变革是将来会提高还是削弱有机合成的效率和优雅性。本文提供了简短的论文，涵盖了逆合成的概念以及示例性的方法和理论，并试图理解在自由和可商购的逆合成和前向合成计划程序日益普及的时代中人工智能的影响。计算机会与人类的逆合成设计和有机合成技术竞争吗？