A 63-year-old woman presented as a thrombolysis call with dysarthria, diplopia, vertigo and generalised weakness. She had a history of high-grade serous ovarian cancer, treated 3 years previously with surgery and chemotherapy and believed to be in remission. She also had osteoarthritis of the hips. On examination, there was mild dysarthria, abnormal eye movements in horizontal and vertical planes and generalised limb weakness. MR scan of brain without contrast was normal. The initial diagnosis on the stroke unit was of benign paroxysmal positional vertigo with lower limb weakness exacerbated by hip pain, and probable functional overlay. An Epley manoeuvre gave only minimal clinical benefit. The neurology team assessed her and noted several weeks of progressively slurred speech, oscillopsia, reduced upper limb coordination and unsteady gait. On examination, she had cerebellar dysarthria with frank …

中文翻译：

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继发于卵巢癌的副肿瘤性视阵挛-肌阵挛-共济失调综合征

一名 63 岁的女性因溶栓而出现构音障碍、复视、眩晕和全身无力。她有高级别浆液性卵巢癌病史，3 年前接受过手术和化疗，据信处于缓解期。她还患有臀部骨关节炎。检查时，有轻度构音障碍、水平和垂直平面的眼球运动异常和全身四肢无力。没有对比的脑部 MR 扫描是正常的。卒中单元的初步诊断是良性阵发性位置性眩晕，下肢无力因髋部疼痛而加剧，并且可能存在功能重叠。Epley 操作仅提供了最小的临床益处。神经病学小组对她进行了评估，并注意到她数周的言语逐渐含糊、震颤、上肢协调能力下降和步态不稳。