Deep eutectic solvents improve the stability of forsythoside A,Journal of Food Safety

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Deep eutectic solvents improve the stability of forsythoside A
Journal of Food Safety ( IF 1.9 ) Pub Date : 2021-05-13 , DOI: 10.1111/jfs.12907
Qin Zhang ₁ , Zhe Dong ₁ , Huizhi Du ₁

Affiliation

Forsythoside A is used as the main chemical marker for quality control of Forsythia suspensa (Thunb.) Vahl (F. suspensa, Lianqiao in Chinese) fruits and leaves. The hydrolysis of forsythoside A at high temperature and effects of deep eutectic solvents (DESs) on stability of forsythoside A were studied in the article. Forsythoside A, I, and H may be directly converted into each other at high temperature. With more heating time, they are gradually decomposed into smaller molecular compounds. High temperature, alkaline conditions, high humidity, the oxidant, and light drastically destroyed stability of forsythoside A, while acidic conditions and the antioxidant protected it. Compared with water and alcohol solvents, DESs improved effectively stability of forsythoside A due to the formation of hydrogen bonds between DESs and forsythoside A. Our research preliminarily uncovered the converting mechanism of forsythoside A and confirmed that DES improved the stability of forsythoside A.

中文翻译：

低共熔溶剂提高连翘酯苷 A 的稳定性

连翘苷 A 被用作质量控制的主要化学标志物Forsythia suspensa (Thunb.) Vahl ( F. suspensa, lianqiao in Chinese) 水果和树叶。研究了连翘酯苷A在高温下的水解作用以及深共熔溶剂(DESs)对连翘酯苷A稳定性的影响。连翘苷 A、I 和 H 在高温下可直接相互转化。随着加热时间的延长，它们逐渐分解成更小的分子化合物。高温、碱性条件、高湿度、氧化剂和光极大地破坏了连翘苷 A 的稳定性，而酸性条件和抗氧化剂保护了它。DESs与连翘酯苷A之间形成氢键，与水和醇类溶剂相比，DESs有效提高了连翘酯苷A的稳定性。

更新日期：2021-05-13

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