Gompertzian tumor growth can be reproduced by mitosis, related to nutrient supply, with local spatial cell correlations. The global energy constraint alone does not reproduce in vivo data by the observed values of the nutrient expenditure for the cell activities. The depletion of the exponential growth, described by the Gompertz law, is obtained by mean field spatial correlations or by a small word network among cells. The well-known interdependence between the two parameters of the Gompertz growth naturally emerges and depends on the cell volume and on the tumor density.

中文翻译：

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营养供应、细胞空间相关性和 Gompertzian 肿瘤生长

Gompertzian 肿瘤生长可以通过有丝分裂复制，与营养供应有关，具有局部空间细胞相关性。单独的全局能量约束不能通过观察到的细胞活动养分消耗值来再现体内数据。由 Gompertz 定律描述的指数增长的消耗是通过平均场空间相关性或通过细胞之间的小字网络获得的。众所周知，Gompertz 生长的两个参数之间的相互依赖关系自然而然地出现，并且取决于细胞体积和肿瘤密度。