COVID-19 is considered by the World Health Organization to be a global public health emergency, which presents regional divergences that affect the epidemiological profile of the disease and are associated with political, economic, social and behavioral aspects. We aimed to analyze the epidemiological characteristics of the disease in the microregion of Uberlândia, Brazil, in order to determine risk factors that contributed to progression of SARS-CoV-2 virus. A cross-sectional study was conducted about micro- and macro-determinants combined with the significance analysis of suspected and confirmed cases in 18 municipalities during the epidemiological weeks (EW) 9 to 26. There were 34,046 notifications, of which 4935 (14.49%) people were diagnosed with COVID-19. Of these, 282 (5.71%) required hospital care and 40 (0.81%) died. Age and presence of associated comorbidities were decisive in the variations of incidence and lethality rates. In general, young people were the most affected and the elderly people, the most exposed to the serious and lethal form (p < 0.0001). Comorbidities such as diabetes and cardiopathies increased 33.5 times the death risk. The dispersion of the virus was centrifugal, in the inter as well as in the intra-municipal level. The disorderly implementation of municipal decrees applied in a decentralized manner in the municipalities seems to have contributed for the incidence rates increasing in the EW 25 and 26.

中文翻译：

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巴西米纳斯吉拉斯州 (MG) 乌贝兰迪亚微地区 COVID-19 初始演变的流行病学方面

COVID-19 被世界卫生组织认为是全球突发公共卫生事件，它呈现出影响该疾病流行病学特征的区域差异，并与政治、经济、社会和行为方面相关。我们的目的是分析巴西乌贝兰迪亚小区域该疾病的流行病学特征，以确定导致 SARS-CoV-2 病毒进展的危险因素。对微观和宏观决定因素进行了横断面研究，并结合流行病学周（EW）9至26期间18个城市的疑似病例和确诊病例的显着性分析。共有34,046份通报，其中4935份（14.49%）人们被诊断出患有 COVID-19。其中，282 人（5.71%）需要住院治疗，40 人（0.81%）死亡。年龄和相关合并症的存在对于发病率和死亡率的变化具有决定性作用。一般来说，年轻人受影响最严重，老年人最容易受到严重和致命的形式的影响（p < 0.0001）。糖尿病和心脏病等合并症使死亡风险增加 33.5 倍。病毒在市内和市内的传播都是离心式的。各城市以分散方式实施的市政法令的无序执行似乎是 EW 25 和 26 地区发病率上升的原因之一。