Abstract

Cell carriers such as chitosan, alginate and cellulose play a crucial role in cell behavior, however the influence of their chemical nature on osteogenesis is little studied. Here, rat bone marrow cells were grown on the surface of those polymers. The cells remained viable and produced a mineral matrix, which was deposited on the surface of all the polymers. The amount of inorganic matrix significantly varied according to the polymer, and the morphology of the inorganic matrix was influenced by the nature of the substrates, generating perfect hexagonal crystals at the surface of chitosan, alginate and cellulose.

中文翻译：

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壳聚糖、纤维素和藻酸盐化学性质对矿物基质形成的影响

摘要

壳聚糖、藻酸盐和纤维素等细胞载体在细胞行为中起着至关重要的作用，但它们的化学性质对成骨的影响研究很少。在这里，大鼠骨髓细胞在这些聚合物的表面上生长。细胞保持活力并产生矿物基质，沉积在所有聚合物的表面上。无机基质的量因聚合物而异，无机基质的形态受基质性质的影响，在壳聚糖、海藻酸盐和纤维素的表面产生完美的六方晶体。