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Disconnection of posterior part of the frontal aslant tract causes acute phase motor functional deficit
Brain and Cognition ( IF 2.5 ) Pub Date : 2021-05-14 , DOI: 10.1016/j.bandc.2021.105752
Riho Nakajima 1 , Masashi Kinoshita 2 , Hirokazu Okita 3 , Harumichi Shinohara 4 , Mitsutoshi Nakada 2
Affiliation  

The frontal aslant tract (FAT) mainly connects the supplementary motor area (SMA) and inferior frontal gyrus. The left FAT is involved in language-related functions, while the functional role of the right FAT is not fully understood. The aim of this study was to investigate the function of the right FAT by dividing it into three segments according to the anatomical structure. A total of 34 right frontal gliomas who had undergone surgery were studied. Participants were assessed for the acute and chronic phases of several neuropsychological and motor functions. FAT was reconstructed into the anterior, middle, and posterior segments according to the cortical connections as the medial prefrontal cortex, pre-SMA, and SMA proper, respectively. The relationships between the damaged severity of each FAT segment and behavioral scores were analyzed. A significant relationship was observed only in the acute phase motor function and posterior segment of the FAT. The middle segment was involved in motor function, but it did not have a sufficient significance level compared to the posterior segment. Our study revealed that the right FAT can be divided into three segments and that its posterior segment is related to acute phase motor function.



中文翻译:

额叶后部的脱节导致急性期运动功能障碍

额叶斜道(FAT)主要连接辅助运动区(SMA)和额下回。左FAT涉及与语言相关的功能,而右FAT的功能角色尚不完全清楚。这项研究的目的是通过根据解剖结构将其分为三个部分来研究右FAT的功能。共对34例接受手术的右额神经胶质瘤进行了研究。评估参与者的几种神经心理学和运动功能的急性和慢性阶段。根据分别作为内侧前额叶皮层,前SMA和SMA固有的皮质连接,将FAT重建为前,中和后节。分析了每个FAT段的损坏严重程度与行为评分之间的关​​系。仅在急性期运动功能和FAT的后段中观察到显着的关系。中段参与了运动功能,但与后段相比没有足够的显着性水平。我们的研究表明,右FAT可分为三个部分,其后部分与急性期运动功能有关。

更新日期:2021-05-14
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