Enteroviruses (EV) have been linked to lymphocytic meningitis and exanthems, but they may also be involved in acute gastroenteritis (AGE), a condition whose aetiological agent often remains unidentified. In this work 1214 samples from individuals with AGE were studied with the aim of establishing the incidence of EV. The samples were collected between September and December in three different years and subjected to real-time genomic amplification in order to determine the viral load (VL). Of the 1214 samples studied, infection by a single virus was found in 328 cases (27%) and coinfection in 69 (5.7%). While adenoviruses (AdV) were the most frequent (14.8% of total), EV were present in 126 (10.4%) of the individuals tested. Of the 126 EV-positive samples, this virus was found as a single infection and coinfection in 76 (6.3%) and 50 (4.1%) cases, respectively. VL for EV was 5.58±1.51 log copies/ml (range 3.73–9.69) in the former and 6.27±1.75 (range 3.73–10.5) (p=0.02) in the latter. EV were identified in 97 children under 5 (16.9%) and in 29 (4.5%) patients over 5. Patients less than 5 years showed a higher VL that those more than 5 years age [6.08±1.57 (range 3.82–9.69) vs. 5.07±1.53 (range 3.73–10.58); (p=0.002)]. There was a high incidence of EV in AGE patients, and they were more frequent in those under 5, where they were found to replicate more efficiently. These results therefore indicate that testing for EV should be included in the diagnosis of AGE.

肠道病毒 (EV) 与淋巴细胞性脑膜炎和皮疹有关，但它们也可能与急性胃肠炎 (AGE) 相关，这种疾病的病因通常仍未确定。在这项工作中，研究了来自 AGE 个体的 1214 个样本，目的是确定 EV 的发病率。样本是在三个不同年份的 9 月和 12 月之间收集的，并进行实时基因组扩增以确定病毒载量 (VL)。在研究的 1214 个样本中，328 例 (27%) 发现单一病毒感染，69 例 (5.7%) 合并感染。虽然腺病毒 (AdV) 是最常见的（占总数的 14.8%），但在 126 名（10.4%）的测试个体中存在 EV。在 126 份 EV 阳性样本中，发现该病毒为单一感染和 76 例（6.3%）和 50 例（4.1%）病例的合并感染，分别。EV 的 VL 前者为 5.58±1.51 log 拷贝/ml（范围 3.73-9.69），后者为 6.27±1.75（范围 3.73-10.5）（p=0.02）。在 97 名 5 岁以下儿童 (16.9%) 和 29 名 (4.5%) 5 岁以上患者中发现了 EV。 5 岁以下患者的 VL 高于 5 岁以上患者 [6.08±1.57（范围 3.82-9.69）vs . 5.07±1.53（范围3.73-10.58）；(p=0.002)]。AGE 患者中 EV 的发生率很高，并且在 5 岁以下的患者中更频繁，发现它们更有效地复制。因此，这些结果表明 EV 的检测应包括在 AGE 的诊断中。5岁以下患者的VL高于5岁以上患者[6.08±1.57（范围3.82-9.69）vs. 5.07±1.53（范围3.73-10.58）；(p=0.002)]。AGE 患者中 EV 的发生率很高，并且在 5 岁以下的患者中更频繁，发现它们更有效地复制。因此，这些结果表明 EV 的检测应包括在 AGE 的诊断中。5岁以下患者的VL高于5岁以上患者[6.08±1.57（范围3.82-9.69）vs. 5.07±1.53（范围3.73-10.58）；(p=0.002)]。AGE 患者中 EV 的发生率很高，并且在 5 岁以下的患者中更频繁，发现它们更有效地复制。因此，这些结果表明 EV 的检测应包括在 AGE 的诊断中。