Individuals with a history of low maternal care (MC) frequently present a blunted, yet sometimes also show an increased cortisol stress response. Fasted individuals with low blood glucose levels who are exposed to acute stress typically show an attenuated response pattern in this endocrine marker. Despite well-documented metabolic dysregulations after low MC, a possible interaction of both factors has not been investigated yet. Here, we examined the effects of MC and blood glucose concentration on various aspects of the stress response. Fasted women (N = 122, mean_age = 22.12, sd_age = 2.56) who experienced either very high, high, or low MC (based on the Parental Bonding Instrument) were randomly assigned to consume grape juice (condition sugar), or water (condition water) prior to being exposed to the Trier-Social-Stress-Test for groups. Salivary cortisol and alpha amylase, blood glucose, and mood ratings were assessed repeatedly. Using multilevel mixed models, we replicated the boosting effect of glucose on the cortisol stress response. While we found neither an effect of MC, nor an interaction between MC and blood glucose availability on the cortisol stress response, we observed an effect of MC on the amylase stress response. We discuss the results in the light of links between various stress/energy systems that possibly mediate health-related MC effects.

具有低产妇护理 (MC) 历史的个体经常表现出迟钝，但有时也表现出皮质醇应激反应增加。暴露于急性压力的低血糖水平的禁食个体通常在这种内分泌标志物中表现出减弱的反应模式。尽管在低 MC 后有充分记录的代谢失调，但尚未研究这两种因素的可能相互作用。在这里，我们检查了 MC 和血糖浓度对应激反应各个方面的影响。禁食妇女（N  = 122，平均_年龄 = 22.12，标准差_年龄 = 2.56）经历了非常高、高或低 MC（基于父母结合工具）被随机分配饮用葡萄汁（条件糖) 或水（条件水）在被暴露于团体的 Trier-Social-Stress-Test 之前。唾液皮质醇和α淀粉酶、血糖和情绪等级被反复评估。使用多级混合模型，我们复制了葡萄糖对皮质醇应激反应的促进作用。虽然我们既没有发现 MC 的影响，也没有发现 MC 和血糖可用性之间的相互作用对皮质醇应激反应的影响，但我们观察到 MC 对淀粉酶应激反应的影响。我们根据可能介导健康相关 MC 效应的各种压力/能量系统之间的联系来讨论结果。