Hypertrophic cardiomyopathy (HCM) is clinically diagnosed when there is unexplained left ventricular (LV) wall thickness of 15 mm or greater. However, clinical diagnosis of HCM is neither specific (owing to the presence of phenocopy) nor sensitive (owing to incomplete penetrance of causal variants). Distinguishing HCM from phenocopies is important because treatment may differ substantially.

This case series describes a 33-year-old woman who was 30 weeks pregnant, with 2 prior uncomplicated pregnancies, and was admitted for hypotension. The Advocate Aurora Health institutional review board approved the study, and oral informed consent was obtained from the patient. This study was performed from June 30, 2018, to July 24, 2020, and followed the reporting guideline for case series.

当无法解释的左心室 (LV) 壁厚 15 mm 或更大时，临床诊断为肥厚性心肌病 (HCM)。然而，HCM 的临床诊断既不特异（由于存在表型检查）也不敏感（由于因果变异的不完全外显率）。区分 HCM 和 phenocopies 很重要，因为治疗可能有很大差异。

本病例系列描述了一名 33 岁女性，她怀孕 30 周，之前有 2 次无并发症的妊娠，因低血压入院。Advocate Aurora Health 机构审查委员会批准了该研究，并获得了患者的口头知情同意。本研究于 2018 年 6 月 30 日至 2020 年 7 月 24 日进行，并遵循病例系列报告指南。