Dorsal raphe serotonergic neurons promote arousal from isoflurane anesthesia,CNS Neuroscience & Therapeutics

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Dorsal raphe serotonergic neurons promote arousal from isoflurane anesthesia
CNS Neuroscience & Therapeutics ( IF 4.8 ) Pub Date : 2021-05-11 , DOI: 10.1111/cns.13656
Ao Li ₁ , Rui Li ₁ , Pengrong Ouyang ₁ , Huihui Li ₁ , Sa Wang ₁ , Xinxin Zhang ₁ , Dan Wang ₁ , Mingzi Ran ₁ , Guangchao Zhao ₁ , Qianzi Yang ₁ , Zhenghua Zhu ₁ , Hailong Dong ₁ , Haopeng Zhang ₁

Affiliation

General anesthesia has been widely applied in surgical or nonsurgical medical procedures, but the mechanism behind remains elusive. Because of shared neural circuits of sleep and anesthesia, whether serotonergic system, which is highly implicated in modulation of sleep and wakefulness, regulates general anesthesia as well is worth investigating.

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