Abstract

The micro- and sub-microstructures of human cortical bone are analytically investigated in this study. Modified equations are derived as a function of sub-microstructural architectures and volumetric bone mineral density (BMD) in order to estimate the nine orthotropic elastic constants of cortical bone at sub-microlevel. In general, the analytical models contain fanning or oscillating plywood layup at the lamella level are in good agreement with the results of nanoindentation tests, and the osteon models contain combinations of twisting/oscillating or unidirectional/fanning lamellar patterns are in agreement with the experimental results of direct tensile and punching shear tests on a single osteon.

摘要

本研究对人体皮质骨的微观和亚微观结构进行了分析研究。修改后的方程作为亚微结构结构和体积骨矿物质密度 (BMD) 的函数推导出来，以估计亚微水平下皮质骨的九个正交各向异性弹性常数。总的来说，分析模型包含在薄片水平上的扇形或振荡胶合板铺层与纳米压痕测试的结果非常一致，并且包含扭曲/振荡或单向/扇形层状图案组合的骨模型与实验结果一致对单个骨进行直接拉伸和冲切试验。