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Quantum-based exact pattern matching algorithms for biological sequences
ETRI Journal ( IF 1.3 ) Pub Date : 2021-05-11 , DOI: 10.4218/etrij.2019-0589
Kapil Kumar Soni 1 , Akhtar Rasool 1
Affiliation  

In computational biology, desired patterns are searched in large text databases, and an exact match is preferable. Classical benchmark algorithms obtain competent solutions for pattern matching in urn:x-wiley:12256463:media:etr212365:etr212365-math-0001 time, whereas quantum algorithm design is based on Grover's method, which completes the search in urn:x-wiley:12256463:media:etr212365:etr212365-math-0002 time. This paper briefly explains existing quantum algorithms and defines their processing limitations. Our initial work overcomes existing algorithmic constraints by proposing the quantum-based combined exact (QBCE) algorithm for the pattern-matching problem to process exact patterns. Next, quantum random access memory (QRAM) processing is discussed, and based on it, we propose the QRAM processing-based exact (QPBE) pattern-matching algorithm. We show that to find all urn:x-wiley:12256463:media:etr212365:etr212365-math-0003 occurrences of a pattern, the best case time complexities of the QBCE and QPBE algorithms are urn:x-wiley:12256463:media:etr212365:etr212365-math-0004, and the exceptional worst case is bounded by urn:x-wiley:12256463:media:etr212365:etr212365-math-0005. Thus, the proposed quantum algorithms achieve computational speedup. Our work is proved mathematically and validated with simulation, and complexity analysis demonstrates that our quantum algorithms are better than existing pattern-matching methods.

中文翻译:

基于量子的生物序列精确模式匹配算法

在计算生物学中,在大型文本数据库中搜索所需的模式,最好是精确匹配。经典基准算法urn:x-wiley:12256463:media:etr212365:etr212365-math-0001及时获得模式匹配的有效解决方案,而量子算法设计基于格罗弗的方法,urn:x-wiley:12256463:media:etr212365:etr212365-math-0002及时完成搜索。本文简要解释了现有的量子算法并定义了它们的处理限制。我们的初步工作通过针对模式匹配问题提出基于量子的组合精确 (QBCE) 算法来处理精确模式,从而克服了现有的算法约束。接下来,讨论了量子随机存取存储器(QRAM)处理,并在此基础上提出了基于QRAM处理的精确(QPBE)模式匹配算法。我们证明要找到所有urn:x-wiley:12256463:media:etr212365:etr212365-math-0003出现模式时,QBCE 和 QPBE 算法的最佳情况时间复杂度为urn:x-wiley:12256463:media:etr212365:etr212365-math-0004,异常最坏情况的时间复杂度为urn:x-wiley:12256463:media:etr212365:etr212365-math-0005。因此,所提出的量子算法实现了计算加速。我们的工作在数学上得到了证明并通过模拟进行了验证,复杂性分析表明我们的量子算法优于现有的模式匹配方法。
更新日期:2021-06-29
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