miR-4286 functions in osteogenesis and angiogenesis via targeting histone deacetylase 3 and alleviates alcohol-induced bone loss in mice,Cell Proliferation

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miR-4286 functions in osteogenesis and angiogenesis via targeting histone deacetylase 3 and alleviates alcohol-induced bone loss in mice
Cell Proliferation ( IF 5.9 ) Pub Date : 2021-05-10 , DOI: 10.1111/cpr.13054
Hongping Yu _{1,

2} , Kaiyang Wang ₁ , Pei Liu ₁ , Pengbo Luo ₁ , Daoyu Zhu ₁ , Junhui Yin ₃ , Qianhao Yang ₁ , Yigang Huang ₁ , Junjie Gao ₁ , Zisheng Ai ₄ , Yixuan Chen ₁ , Youshui Gao ₁

Affiliation

Alcohol consumption is one of the leading factors contributing to premature osteopenia. MicroRNA (miRNA) coordinates a cascade of anabolic and catabolic processes in bone homeostasis and dynamic vascularization. The aim was to investigate the protective role of miR-4286 in alcohol-induced bone loss and its mechanism.

中文翻译：

miR-4286 通过靶向组蛋白去乙酰化酶 3 在成骨和血管生成中起作用并减轻小鼠酒精诱导的骨质流失

饮酒是导致过早骨质减少的主要因素之一。MicroRNA (miRNA) 协调骨稳态和动态血管形成中的合成代谢和分解代谢过程的级联。目的是研究miR-4286在酒精性骨质流失中的保护作用及其机制。

更新日期：2021-06-01

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