Monocytes, plasmacytoid and conventional dendritic cells are crucial for antiviral immune responses. A new study now compares severe and moderate cases of COVID-19 and links defects in viral sensing, interferon and antigen presentation pathways, associated with upregulated apoptosis and inflammatory pathways, to high COVID-19 severity.

中文翻译：

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COVID-19 中的单核细胞和树突状细胞缺陷


单核细胞、浆细胞样细胞和传统树突状细胞对于抗病毒免疫反应至关重要。一项新的研究现在比较了严重和中度的 COVID-19 病例，并将与细胞凋亡和炎症途径上调相关的病毒传感、干扰素和抗原呈递途径的缺陷与 COVID-19 的高严重程度联系起来。