Background Historical loss in American Indians (AIs) is believed to contribute to high incidence of mental health disorders, yet less is known about the associations between historical loss and physical health. Purpose To investigate whether frequency of thought about historical loss predicts risk factors for chronic physical health conditions in an AI community. Methods Using Community Based Participatory research (CBPR) and Ecological Momentary Assessment (EMA), we measured frequency of thoughts about historical loss in 100 AI adults residing on the Blackfeet reservation. Participants completed a 1-week monitoring period, during which ambulatory blood pressure and daily levels of psychological stress were measured. At the end of the week, we collected a dried blood spot sample for measurement of C-reactive protein (CRP). Results In hierarchical linear regression models controlling for demographics and relevant covariates, greater frequency of thoughts about historical loss predicted higher average daily psychological stress (B = .55, t = 6.47, p < .001, ΔR2 = .30) and higher levels of CRP (B = .33, t = 3.93, p < .001, ΔR2 = .10). Using linear mixed modeling with relevant covariates, we found that greater thoughts about historical loss were associated with higher systolic ambulatory blood pressure (B = .32, 95% CI = .22–.42, t = 6.48, p < .001, ΔR2 = .25; Fig. 1c) and greater diastolic ambulatory blood pressure (B = .19, 95% CI = .11–.27, t = 4.73, p < .001, ΔR2 = .19). Conclusions The data suggest that frequency of thought about historical loss may contribute to increased subclinical risk for cardiovascular disease in the Blackfeet community.

中文翻译：

---

历史损失：对黑脚社区美国印第安人健康的影响

背景 美国印第安人 (AI) 的历史损失被认为是导致精神健康障碍高发的原因，但人们对历史损失与身体健康之间的关联知之甚少。目的 调查对历史损失的思考频率是否可以预测 AI 社区中慢性身体健康状况的风险因素。方法使用基于社区的参与式研究 (CBPR) 和生态瞬时评估 (EMA)，我们测量了居住在 Blackfeet 保留地的 100 名 AI 成年人对历史损失的想法频率。参与者完成了为期 1 周的监测期，在此期间测量了动态血压和每日心理压力水平。在一周结束时，我们收集了一份干血斑样本用于测量 C 反应蛋白 (CRP)。结果 在控制人口统计和相关协变量的分层线性回归模型中，对历史损失的更高频率的想法预示着更高的平均每日心理压力（B = .55，t = 6.47，p <.001，ΔR2 = .30）和更高的水平CRP (B = .33, t = 3.93, p < .001, ΔR2 = .10)。使用具有相关协变量的线性混合模型，我们发现对历史损失的更多想法与更高的收缩期动态血压相关（B = .32, 95% CI = .22–.42, t = 6.48, p <.001, ΔR2 = .25；图 1c) 和更大的舒张期动态血压 (B = .19, 95% CI = .11–.27, t = 4.73, p <.001, ΔR2 = .19)。