Faster disease progression in Parkinson’s disease with type 2 diabetes is not associated with increased α-synuclein, tau, amyloid-β or vascular pathology,Neuropathology and Applied Neurobiology

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Faster disease progression in Parkinson’s disease with type 2 diabetes is not associated with increased α-synuclein, tau, amyloid-β or vascular pathology
Neuropathology and Applied Neurobiology ( IF 4.0 ) Pub Date : 2021-05-09 , DOI: 10.1111/nan.12728
Eduardo de Pablo-Fernández _{1,

2} , Robert Courtney ₁ , Alice Rockliffe ₁ , Steve Gentleman ₃ , Janice L Holton ₁ , Thomas T Warner _{1,

2}

Affiliation

Growing evidence suggests a shared pathogenesis between Parkinson's disease and diabetes although the underlying mechanisms remain unknown. The aim of this study was to evaluate the effect of type 2 diabetes on Parkinson's disease progression and to correlate neuropathological findings to elucidate pathogenic mechanisms.

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