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Faster disease progression in Parkinson’s disease with type 2 diabetes is not associated with increased α-synuclein, tau, amyloid-β or vascular pathology
Neuropathology and Applied Neurobiology ( IF 4.0 ) Pub Date : 2021-05-09 , DOI: 10.1111/nan.12728 Eduardo de Pablo-Fernández 1, 2 , Robert Courtney 1 , Alice Rockliffe 1 , Steve Gentleman 3 , Janice L Holton 1 , Thomas T Warner 1, 2
Neuropathology and Applied Neurobiology ( IF 4.0 ) Pub Date : 2021-05-09 , DOI: 10.1111/nan.12728 Eduardo de Pablo-Fernández 1, 2 , Robert Courtney 1 , Alice Rockliffe 1 , Steve Gentleman 3 , Janice L Holton 1 , Thomas T Warner 1, 2
Affiliation
Growing evidence suggests a shared pathogenesis between Parkinson's disease and diabetes although the underlying mechanisms remain unknown. The aim of this study was to evaluate the effect of type 2 diabetes on Parkinson's disease progression and to correlate neuropathological findings to elucidate pathogenic mechanisms.
中文翻译:
帕金森病伴 2 型糖尿病的疾病进展较快与 α-突触核蛋白、tau、β-淀粉样蛋白或血管病理学增加无关
越来越多的证据表明帕金森病和糖尿病之间存在共同的发病机制,尽管其潜在机制仍然未知。本研究的目的是评估 2 型糖尿病对帕金森病进展的影响,并关联神经病理学发现以阐明致病机制。
更新日期:2021-05-09
中文翻译:
帕金森病伴 2 型糖尿病的疾病进展较快与 α-突触核蛋白、tau、β-淀粉样蛋白或血管病理学增加无关
越来越多的证据表明帕金森病和糖尿病之间存在共同的发病机制,尽管其潜在机制仍然未知。本研究的目的是评估 2 型糖尿病对帕金森病进展的影响,并关联神经病理学发现以阐明致病机制。