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Sex differences in the neuropathological hallmarks of Alzheimer’s disease: focus on cognitively intact elderly individuals
Neuropathology and Applied Neurobiology ( IF 5 ) Pub Date : 2021-05-09 , DOI: 10.1111/nan.12729
Yu-Ting Hu 1, 2 , Jackson Boonstra 3 , Hugo McGurran 3 , Jochem Stormmesand 3 , Arja Sluiter 3 , Rawien Balesar 3 , Ronald Verwer 3 , Dick Swaab 1, 2, 3 , Ai-Min Bao 1, 2
Affiliation  

Women are more vulnerable to Alzheimer's disease (AD) than men. We investigated (i) whether and at what age the AD hallmarks, that is, β-amyloid (Aβ) and hyperphosphorylated Tau (p-Tau) show sex differences; and (ii) whether such sex differences may occur in cognitively intact elderly individuals.

中文翻译:

阿尔茨海默病神经病理学特征的性别差异:关注认知完整的老年人

女性比男性更容易患阿尔茨海默病 (AD)。我们调查了 (i) AD 标志物,即 β-淀粉样蛋白 (Aβ) 和过度磷酸化 Tau (p-Tau) 是否以及在什么年龄显示出性别差异;(ii) 这种性别差异是否可能发生在认知完整的老年人身上。
更新日期:2021-05-09
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