The effect of the composition of polymeric compositions and the pH of the solutions on the properties of active films from covalently linked chitosan (the kinetics of swelling and biodegradation) was studied, and th—e biorelease of medicinal compounds from the cross-linked films was analyzed. It was established that the release of lidocaine from the crosslinked films involves superimposition of kinetic mechanisms with diffusion of molecules of the medicinal compound and its transfer into solution as a result of biodegradation of the chitosan. The investigated systems based on cross-linked chitosan can be used as wound dressings or as fibrous composite materials with prolonged release of medicinal compounds.

研究了聚合物组合物的组成和溶液的pH值对共价连接的壳聚糖活性膜性能（溶胀和生物降解动力学）的影响，并研究了药物从交联膜中的生物释放。分析。已经确定，从交联的膜释放利多卡因涉及动力学机制与药用化合物分子的扩散及其由于壳聚糖的生物降解而转移到溶液中的叠加。基于交联壳聚糖的研究体系可以用作伤口敷料或延长药物成分释放的纤维复合材料。