To evaluate the quality of life (QOL) of children with asthma and analyze the related factors. A total of 360 children diagnosed with asthma were enrolled. We conducted the pediatric asthma quality of life questionnaire (PAQLQ). The differences in clinical characteristics between the two groups were compared. Clinical characteristics were compared between high and low QOL. More female was observed in low QOL group (p = 0.013). Patients with higher income (p = 0.003) were shown with higher QOL. Female patients presented significantly lower values for activity limitation (p = 0.016) and emotional function (p = 0.016) as compared to male patients. For patients who have low income, the QOL scores for dimensions of activity limitation was significantly worse than those have higher income (p = 0.001). Univariable results showed that gender (p = 0.013) and income (p = 0.001) were factors associated with QOL in asthma children. However, multivariate analysis suggested that only gender (OR = 0.558, p = 0.008) and income (OR = 1.762, p < 0.001) were the independent factors that affected the QOL levels. In this study, we found that the QOL dimensions of pediatric asthma differed between various subpopulations. For patients with risk factors of poor QOL, target intervention is advised in order to increase QOL.

评估哮喘儿童的生活质量（QOL）并分析相关因素。共有 360 名被诊断患有哮喘的儿童入组。我们进行了小儿哮喘生活质量问卷（PAQLQ）。比较两组临床特征的差异。比较高生活质量和低生活质量之间的临床特征。在低生活质量组中观察到更多女性（p  = 0.013）。收入较高的患者 ( p  = 0.003) 的生活质量较高。 与男性患者相比，女性患者的活动限制值 ( p  = 0.016) 和情绪功能值 ( p = 0.016)显着较低。对于低收入患者，活动限制维度的生活质量评分显着差于收入较高的患者 ( p  = 0.001)。单变量结果显示，性别（p  = 0.013）和收入（p  = 0.001）是与哮喘儿童生活质量相关的因素。然而，多变量分析表明，只有性别（OR = 0.558，p  = 0.008）和收入（OR = 1.762，p  < 0.001）是影响QOL水平的独立因素。在这项研究中，我们发现儿童哮喘的生活质量维度在不同亚人群之间存在差异。对于存在生活质量较差危险因素的患者，建议进行针对性干预以提高生活质量。