Within the last decade, pelvic organ prolapse (POP) resulting in sow mortality has become an increasing concern for the U.S. swine industry, contributing approximately 21% of all sow deaths. While little is known regarding the etiology preceding POP in sows, many have proposed an association with vitamin and trace minerals abundance to POP incidence. We tested the hypothesis that sows differing in POP risk would have differences in serum trace minerals and vitamins. A perineal scoring (PS) system (PS1 - presumed low risk; PS2 - presumed moderate risk; and PS3 - presumed high risk) to assess risk for POP during late gestation was used to score 213 individual sows. Blood was collected from sows of two different farms during late gestation (days 105–115) that scored a PS3 (n = 20) and a parity matched sow scored as PS 1 (n = 16). Subsequently, 1.5, 0.8, and 23.1% of sows scored as PS1, PS2, or PS3, respectively, experienced POP. Serum was analyzed at the Iowa State University Veterinary Diagnostic Lab for trace mineral content (Calcium, Copper, Iron, Potassium, Magnesium, Manganese, Molybdenum, Phosphorus, Selenium, and Zinc). Additionally, vitamin E was evaluated in serum via GC-MS. Differences (P < 0.05) in copper, potassium, molybdenum, phosphorus, and selenium was observed between farms. Further a PS x Farm interaction (P = 0.06) was observed for serum copper abundance which across all farms was 12% less (P < 0.04) in PS3 compared to PS1 sows. No impact on serum vitamin E was observed between PS sows. These data demonstrate sows with greater POP risk may have potential differences in serum factors although these data also underscore the importance of measuring vitamin and mineral quantities in a tissue specific manner. This project was supported by the National Pork Board and the Foundation for Food and Agriculture Research.

中文翻译：

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289 妊娠晚期母猪的血清微量矿物质有不同的盆腔器官脱垂风险

在过去十年中，导致母猪死亡的盆腔器官脱垂 (POP) 已成为美国养猪业日益关注的问题，约占所有母猪死亡的 21%。虽然对母猪 POP 之前的病因知之甚少，但许多人提出维生素和微量矿物质丰度与 POP 发病率有关。我们检验了以下假设，即具有不同 POP 风险的母猪在血清微量矿物质和维生素方面存在差异。使用会阴评分 (PS) 系统（PS1 - 假定为低风险；PS2 - 假定为中度风险；和 PS3 - 假定为高风险）评估妊娠晚期 POP 的风险，对 213 头母猪进行评分。在妊娠后期（第 105-115 天）从两个不同农场的母猪采集血液，这些母猪的评分为 PS3（n = 20），胎次匹配的母猪评分为 PS 1（n = 16）。随后，1.5, 0。得分为 PS1、PS2 或 PS3 的母猪中分别有 8 和 23.1% 的母猪经历了 POP。在爱荷华州立大学兽医诊断实验室对血清进行了微量矿物质含量分析（钙、铜、铁、钾、镁、锰、钼、磷、硒和锌）。此外，通过 GC-MS 评估血清中的维生素 E。观察到农场之间铜、钾、钼、磷和硒的差异（P < 0.05）。此外，观察到血清铜丰度的 PS x 农场相互作用 (P = 0.06)，与 PS1 母猪相比，在所有农场中，PS3 母猪的血清铜丰度低 12% (P < 0.04)。在 PS 母猪之间未观察到对血清维生素 E 的影响。这些数据表明，具有较高 POP 风险的母猪可能在血清因子方面存在潜在差异，尽管这些数据也强调了以组织特异性方式测量维生素和矿物质含量的重要性。该项目得到了国家猪肉委员会和粮食和农业研究基金会的支持。