Pronouns constitute a heterogeneous class of linguistic elements, allowing for expression of referential relationships. Pronouns have an important place in daily communication which speakers and listeners rely heavily on for. Aphasia literature has evidenced that pronoun processing is impaired in people with aphasia (PWA), although explanations underpinning pronoun impairments are mixed. To address this, through a systematic literature review, we identified 42 studies which examined pronoun processing (both production and comprehension) in 474 PWA across 16 different languages. An initial meta-analysis was conducted on the overall data with all PWA and pronoun conditions with an outcome measure indicating whether or not pronoun processing is individually impaired in PWA. Further meta-analytic models were built to compare certain conditions of particular interest (e.g. reflexives vs object pronouns, object vs subject wh-pronouns) in an attempt to further disentangle the explanations behind their difficulty in use. Outputs from our meta-analysis suggest that: (i) a form of pronoun impairment is consistently present in aphasia regardless of aphasia type, fluency or language spoken; (ii) pronoun variables show selectivity in their impairment, for instance, reflexives are better preserved over object pronouns, and the subject-advantage in who-pronouns is language-selective; and (iii) other important linguistic variables that largely predict pronoun impairments include aspects like argument position of subject/object phrases, case marking, cliticization, and the presence of relative clause constructions. These outputs are discussed in relation to neurolinguistic hypotheses that predict pronoun impairments in aphasia.

代词构成一类异类的语言元素，可以表达参照关系。代词在日常交流中具有重要的地位，而说话者和听众会严重依赖代词。失语症文献已经证明，尽管支持代词障碍的解释多种多样，但失语症患者（PWA）的代词加工能力受到了损害。为了解决这个问题，我们通过系统的文献综述，确定了42项研究，研究了474种PWA中16种不同语言的代词加工（产生和理解）。对所有PWA和代词条件的整体数据进行了初步的荟萃分析，并通过结果度量表明了PWA中代词的加工是否受到单独的损害。（wh-代词），以试图进一步弄清它们在使用中的困难背后的解释。我们的荟萃分析的结果表明：（i）失语症持续存在一种代词障碍形式，无论失语症的类型，流利程度或所讲的语言如何；（ii）代词变量在其损伤中表现出选择性，例如，反身词比宾语代词更好地被保留，而代词变量的主语优势是语言选择的；（iii）可以很大程度上预测代词损害的其他重要语言变量包括诸如主语/宾语短语的论点位置，格标记，句法和相关从句结构的存在等方面。这些输出是与预测失语代词损伤的神经语言假设有关的。