Batch processes are inevitably affected by disturbances. The process control system can often reject them and ensure that the final product is “in spec.” Nevertheless, processing times and the quality of the final product and any intermediates can fluctuate as a result. In turn, this impacts the computation and execution of production schedules. We propose a new scheduling framework that considers the effect of disturbances and the impact of process control on short-term production scheduling of batch processes. Processing time expressions are derived using historical closed-loop process operating data. Subsequently, a two-stage stochastic scheduling problem is formulated, whereby exogenous and endogenous uncertainties are considered at the first stage, with the exception of product demand, which is dealt with in the second stage. Two case studies are presented in detail.

批处理不可避免地受到干扰的影响。过程控制系统通常可以拒绝它们并确保最终产品“符合规格”。然而，加工时间和最终产品和任何中间体的质量可能会因此而波动。反过来，这会影响生产计划的计算和执行。我们提出了一种新的调度框架，该框架考虑了干扰的影响和过程控制对批处理过程的短期生产调度的影响。处理时间表达式是使用历史闭环过程操作数据导出的。随后，制定了一个两阶段随机调度问题，其中在第一阶段考虑了外生和内生的不确定性，除了在第二阶段处理的产品需求。