Inflammatory bowel disease (IBD) is a chronic inflammatory disease affecting various parts of the gastrointestinal tract. A majority of the current evidence points out the involvement of intestinal dysbiosis in the IBD pathogenesis. Recently, the association of intestinal fungal composition With IBD susceptibility and severity has been reported. These studies suggested gene polymorphisms in the front line of host defense against intestinal microorganisms are considered to play a role in IBD pathogenesis. The studies have also detected increased susceptibility to fungal infections in patients carrying IBD-related mutations. Therefore, a literature search was conducted in related databases to review articles addressing the mycobiota-genotype association in IBD.

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真菌菌群-基因型关联在炎症性肠病中的作用：叙事综述

炎性肠病（IBD）是一种慢性炎性疾病，会影响胃肠道的各个部位。当前的大多数证据指出肠营养不良与IBD发病机制有关。最近，已经报道了肠道真菌组成与IBD易感性和严重性的关系。这些研究表明，宿主抗肠道微生物防御的一线基因多态性被认为在IBD发病机理中起作用。这项研究还发现携带IBD相关突变的患者对真菌感染的敏感性增加。因此，在相关数据库中进行了文献检索，以审查针对IBD中的菌群-基因型关联的文章。