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Hypoxia-inducible factor-1α-mediated upregulation of CD99 promotes the proliferation of placental mesenchymal stem cells by regulating ERK1/2.
World Journal of Stem Cells ( IF 3.6 ) Pub Date : 2021-5-8 , DOI: 10.4252/wjsc.v13.i4.317 Xu-Dong Feng 1 , Jia-Qi Zhu 1 , Jia-Hang Zhou 1 , Fei-Yan Lin 1 , Bing Feng 1 , Xiao-Wei Shi 1 , Qiao-Ling Pan 1 , Jiong Yu 1 , Lan-Juan Li 1 , Hong-Cui Cao 1
World Journal of Stem Cells ( IF 3.6 ) Pub Date : 2021-5-8 , DOI: 10.4252/wjsc.v13.i4.317 Xu-Dong Feng 1 , Jia-Qi Zhu 1 , Jia-Hang Zhou 1 , Fei-Yan Lin 1 , Bing Feng 1 , Xiao-Wei Shi 1 , Qiao-Ling Pan 1 , Jiong Yu 1 , Lan-Juan Li 1 , Hong-Cui Cao 1
Affiliation
As human placenta-derived mesenchymal stem cells (hP-MSCs) exist in a physiologically hypoxic microenvironment, various studies have focused on the influence of hypoxia. However, the underlying mechanisms remain to be further explored.
中文翻译：
缺氧诱导因子-1α介导的CD99上调通过调节ERK1/2促进胎盘间充质干细胞的增殖。
由于人胎盘源性间充质干细胞（hP-MSCs）存在于生理缺氧的微环境中，因此各种研究都集中在缺氧的影响上。然而，其潜在机制仍有待进一步探讨。
更新日期：2021-05-09
中文翻译：
缺氧诱导因子-1α介导的CD99上调通过调节ERK1/2促进胎盘间充质干细胞的增殖。
由于人胎盘源性间充质干细胞（hP-MSCs）存在于生理缺氧的微环境中，因此各种研究都集中在缺氧的影响上。然而，其潜在机制仍有待进一步探讨。
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