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Orthobiologics in the treatment of hip disorders.
World Journal of Stem Cells ( IF 3.6 ) Pub Date : 2021-5-8 , DOI: 10.4252/wjsc.v13.i4.304
André Vinícius Saueressig Kruel 1 , Lucas Leite Ribeiro 2 , Paulo David Gusmão 3 , Stephany Cares Huber 4 , José Fábio Santos Duarte Lana 5
Affiliation  

Orthobiologics are biological materials that are intended for the regeneration or healing of bone, cartilage and soft tissues. In this review we discuss the use of orthobiologics for hip disorders providing an update. The orthobiologics included in this article are hyaluronic acid, platelet rich plasma, bone marrow, adipose tissue and expanded mesenchymal stem cells. We explain the concepts and definitions of each orthobiological product, and the literature regarding its use in the hip joint. The paucity of guidelines for the production and characterization of the biological products leads to uneven results across the literature. Each biologic therapy has indications and benefits; however, noteworthy are the characterization of the orthobiologics, the application method and outcome analysis for further improvement of each technique.

中文翻译:

矫正髋关节疾病的骨科药物。

骨生物制品是旨在用于骨骼,软骨和软组织的再生或愈合的生物材料。在这篇综述中,我们讨论了使用人工生物药物治疗髋关节疾病的最新情况。本文中包含的骨生物制品是透明质酸,富含血小板的血浆,骨髓,脂肪组织和扩增的间充质干细胞。我们将解释每种矫形产品的概念和定义,以及有关其在髋关节中使用的文献。生物制品的生产和表征指南的缺乏导致了整个文献的不均衡结果。每种生物疗法都有适应症和益处;然而,值得注意的是骨科的特性,应用方法和对每种技术的进一步改进的结果分析。
更新日期:2021-05-09
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