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Analysis of the density and distribution of entropy in biomedical infrared imaging for Diabetes Mellitus Type II
Biomedical Physics & Engineering Express Pub Date : 2021-05-18 , DOI: 10.1088/2057-1976/abfea9
Rosalinda Ortiz-Sosa 1, 2 , Edgar Israel Fuentes-Oliver 2 , Crescencio García-Segundo 2 , Raúl Serrano-Loyola 3 , Rebeca Solalinde-Vargas 3
Affiliation  

We report a methodology to analyze data extracted from infrared images. These pictures show the lower limbs of a cohort of individuals belonging to, (1) voluntary controls and (2) patients diagnosed with diabetes mellitus type II. The analysis is presented in terms of Cross Entropy and temperature distributions; both using the associated thermal histograms. The temperature analysis is placed in terms of comparing the extreme values of dS/dQ, for controls and patients. In this analysis for the frontal view, the values of specificity and sensitivity calculated were 77.77% and 91.66%, respectively. For the back view, the specificity and sensitivity obtained were 88.8% and 83.3%, respectively. Instead of that, the cross-entropy analysis is placed in the modality of self-referencing. In this part of the study we obtained the coefficient of asymmetry and thermal response (ATR). The values of specificity and sensitivity for the ATR quotient in both cases were 83.3%. The results of both studies have a significant correlation with glucose (p < 0.01) and HbA1c (p < 0.01). It means that both approaches have statistical correspondence. By means of the Mann-Whitney U test, for independent samples, we get that the characteristic parameters we analyze can be differentiated among the populations of interest with a significance of p < 0.05. This suggests that both studies show consistency with the clinical diagnosis; exhibiting clear differences between control and patient groups.



中文翻译:

II型糖尿病生物医学红外成像熵密度及分布分析

我们报告了一种分析从红外图像中提取的数据的方法。这些图片显示了属于(1)自愿对照和(2)诊断为 II 型糖尿病患者的一组个体的下肢。分析以交叉熵和温度分布的形式呈现;两者都使用相关的热直方图。温度分析是根据比较dS / dQ的极值进行的,用于对照和患者。在该正面视图分析中,计算的特异性和敏感性值分别为 77.77% 和 91.66%。对于后视图,获得的特异性和敏感性分别为 88.8% 和 83.3%。取而代之的是,交叉熵分析被置于自我引用的模式中。在这部分研究中,我们获得了不对称系数和热响应 (ATR)。两种情况下 ATR 商的特异性和敏感性值为 83.3%。两项研究的结果与葡萄糖(p < 0.01)和 HbA1c(p< 0.01)。这意味着两种方法都具有统计对应性。通过 Mann-Whitney U 检验,对于独立样本,我们得到我们分析的特征参数可以在感兴趣的群体中区分,显着性为p < 0.05。这表明两项研究均与临床诊断一致;对照组和患者组之间表现出明显的差异。

更新日期:2021-05-18
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