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Dose-area product ratio in external small-beam radiotherapy: beam shape, size and energy dependencies in clinical photon beams
Biomedical Physics & Engineering Express ( IF 1.3 ) Pub Date : 2021-05-07 , DOI: 10.1088/2057-1976/abf6aa
Jarkko Niemelä 1, 2, 3 , Mari Partanen 4, 5 , Jarkko Ojala 4, 5 , Mika Kapanen 4, 5 , Jani Keyriläinen 2, 3
Affiliation  

In small-field radiotherapy (RT), a significant challenge is to define the amount of radiation dose absorbed in the patient where the quality of the beam has to be measured with high accuracy. The properties of a proposed new beam quality specifier, namely the dose-area-product ratio at 20 and 10 cm depths in water or DAPR20,10, were studied to yield more information on its feasibility over the conventional quality specifier tissue-phantom ratio or TPR20,10. The DAPR20,10 may be measured with a large-area ionization chamber (LAC) instead of small volume chambers or semi-conductors where detector, beam and water phantom positioning and beam perturbations introduce uncertainties. The effects of beam shape, size and energy on the DAPR20,10 were studied and it was shown that the DAPR20,10 increases with increasing beam energy similarly to TPR20,10 but in contrast exhibits a small beam size and shape dependence. The beam profile outside the beam limiting devices has been shown to have a large contribution to the DAPR20,10. There is potential in large area chambers to be used in DAPR measurement and its use in dosimetry of small-beam RT for beam quality measurements.



中文翻译:

外部小束放射治疗中的剂量面积乘积比:临床光子束中的束形状、大小和能量依赖性

在小场放射治疗 (RT) 中,一个重大挑战是定义患者吸收的辐射剂量,其中必须以高精度测量光束质量。对提出的新光束质量说明符的特性,即水中 20 和 10 厘米深度或 DAPR 20,10的剂量面积积比进行了研究,以产生更多关于其与传统质量说明符组织模型比的可行性的信息或 TPR 20,10。DAPR 20,10可以使用大面积电离室 (LAC) 来测量,而不是使用检测器、光束和水模体定位以及光束扰动引入不确定性的小体积室或半导体。光束形状、尺寸和能量对 DAPR 20,10的影响研究表明,DAPR 20,10与 TPR 20,10类似,随着光束能量的增加而增加,但相比之下,光束尺寸和形状依赖性较小。光束限制装置外的光束轮廓已被证明对 DAPR 20,10有很大的贡献。大面积腔室有潜力用于 DAPR 测量及其在用于光束质量测量的小射束 RT 剂量学中的应用。

更新日期:2021-05-07
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