Purpose The aim of this study was to examine the degree to which quantitative aspects of dosage (dose, dose frequency, and total intervention duration) have been examined in intervention studies for children with developmental language disorder (DLD). Additionally, to establish the optimal quantitative dosage characteristics for phonology, vocabulary, and morphosyntax outcomes. Method This registered review (PROSPERO ID CRD42017076663) adhered to PRISMA guidelines. Search terms were included in seven electronic databases. We included peer-reviewed quasi-experimental, randomized controlled trial or cohort analytical studies, published in any language between January 2006 and May 2020. Included articles reported on participants with DLD (M = 3-18 years); oral language interventions with phonology, vocabulary, or morphosyntax outcomes; and experimental manipulation or statistical analysis of any quantitative aspect of dosage. Studies were appraised using the Cochrane risk-of-bias tool. Results Two hundred forty-four articles reported on oral language interventions with children with DLD in the domains of interest; 13 focused on experimentally/statistically manipulating quantitative aspects of dosage. No article reported phonological outcomes, three reported vocabulary, and eight reported morphosyntax. Dose frequency was the most common characteristic manipulated. Conclusions Research is in its infancy, and significant further research is required to inform speech-language pathologists in practice. Dosage characteristics are rarely adequately controlled for their individual effects to be identified. Findings to date suggest that there is a point in vocabulary and morphosyntax interventions after which there are diminishing returns from additional dosage. If dose is high (number of learning opportunities within a session), then the literature suggests that session frequency can be reduced. Frequent, short sessions (2/3 × per week, approximately 2 min) and less frequent, long sessions (1 × per week, approximately 20 min) have yielded the best outcomes when composite language measures have been used; however, replication and further research are required before clinicians can confidently integrate these findings into clinical practice. Supplemental Material https://doi.org/10.23641/asha.13570934.

中文翻译：

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定量干预剂量对发育性语言障碍儿童口语结果的影响：系统评价和叙事综合。

目的 本研究的目的是检查在对发育性语言障碍 (DLD) 儿童的干预研究中对剂量的定量方面（剂量、剂量频率和总干预持续时间）进行检查的程度。此外，为音系、词汇和形态句法结果建立最佳定量剂量特征。方法 该注册审查 (PROSPERO ID CRD42017076663) 遵守 PRISMA 指南。搜索词包含在七个电子数据库中。我们纳入了 2006 年 1 月至 2020 年 5 月期间以任何语言发表的同行评审的准实验、随机对照试验或队列分析研究。具有音系、词汇或形态句法结果的口语干预；和剂量的任何定量方面的实验操作或统计分析。使用 Cochrane 偏倚风险工具对研究进行评估。结果 244 篇文章报道了在感兴趣的领域对 DLD 儿童进行口语干预；13 专注于实验/统计操作剂量的定量方面。没有文章报告语音结果，三篇报告词汇，八篇报告形态句法。剂量频率是最常见的操纵特征。结论 研究还处于起步阶段，需要进一步的研究来为语言病理学家在实践中提供信息。剂量特征很少被充分控制以识别它们的个体效应。迄今为止的研究结果表明，在词汇和形态句法干预方面存在一定意义，在此之后，额外剂量的回报会递减。如果剂量很高（一次课程中的学习机会数量），则文献表明可以减少课程频率。当使用复合语言测量时，频繁、短时间的会话（每周 2/3 次，大约 2 分钟）和不太频繁的长时间会话（每周 1 次，大约 20 分钟）产生了最好的结果；然而，在临床医生可以自信地将这些发现整合到临床实践中之前，还需要重复和进一步的研究。补充材料 https://doi.org/10.23641/asha.13570934。那么文献表明可以减少会话频率。当使用复合语言测量时，频繁、短时间的会话（每周 2/3 次，大约 2 分钟）和不太频繁的长时间会话（每周 1 次，大约 20 分钟）产生了最好的结果；然而，在临床医生可以自信地将这些发现整合到临床实践中之前，还需要重复和进一步的研究。补充材料 https://doi.org/10.23641/asha.13570934。那么文献表明可以减少会话频率。当使用复合语言测量时，频繁、短时间的会话（每周 2/3 次，大约 2 分钟）和不太频繁的长时间会话（每周 1 次，大约 20 分钟）产生了最好的结果；然而，在临床医生可以自信地将这些发现整合到临床实践中之前，还需要重复和进一步的研究。补充材料 https://doi.org/10.23641/asha.13570934。在临床医生可以自信地将这些发现整合到临床实践中之前，需要进行复制和进一步研究。补充材料 https://doi.org/10.23641/asha.13570934。在临床医生可以自信地将这些发现整合到临床实践中之前，需要进行复制和进一步的研究。补充材料 https://doi.org/10.23641/asha.13570934。