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Using social rank as the lens to focus on the neural circuitry driving stress coping styles.
Current opinion in neurobiology Pub Date : 2021-04-27 , DOI: 10.1016/j.conb.2021.03.007
Katherine B LeClair 1 , Scott J Russo 1
Affiliation  

Social hierarchy position in humans is negatively correlated with stress-related psychiatric disease risk. Animal models have largely corroborated human studies, showing that social rank can impact stress susceptibility and is considered to be a major risk factor in the development of psychiatric illness. Differences in stress coping style is one of several factors that mediate this relationship between social rank and stress susceptibility. Coping styles encompass correlated groupings of behaviors associated with differential physiological stress responses. Here, we discuss recent insights from animal models that highlight several neural circuits that can contribute to social rank-associated differences in coping style.

中文翻译:

以社会等级为视角,关注驱动压力应对方式的神经回路。

人类的社会等级地位与压力相关的精神疾病风险呈负相关。动物模型在很大程度上证实了人类研究,表明社会等级会影响压力敏感性,并被认为是精神疾病发展的主要风险因素。压力应对方式的差异是调节社会等级和压力敏感性之间关系的几个因素之一。应对方式包括与不同生理压力反应相关的相关行为分组。在这里,我们讨论了动物模型的最新见解,这些见解突出了几种神经回路,这些神经回路可能导致应对方式的社会等级相关差异。
更新日期:2021-04-27
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