OBJECTIVE Long-term inhaled corticosteroid (ICS) use in children with asthma causes serious concerns in parents, leading to treatment non-adherence. This study aimed to investigate the effect of maternal anxiety and attitudes on adherence to ICS therapy in children with asthma. METHOD The patient group included the children with mild to moderate persistent asthma, aged 6-11 years. Healthy children in a similar age range were included as a control group. The patient group was divided into two categories (treatment adherent and non-adherent) according to the regularity of ICS use. All patients were assessed with Childhood-Asthma Control Test (C-ACT), and their mothers were assessed using Parent Attitude Research Instrument (PARI) and Beck's Anxiety Inventory (BAI). RESULTS A total of 156 children (age: 7.4 ± 1.4 years, F/M: 71/85) with persistent asthma and 60 healthy children (age: 7.5 ± 1.3 years, F/M:25/35) were included in the study. The rate of adherence in children with asthma was 52.6%. Mothers of non-adherent patients had significantly higher BAI scores than those of the adherent patients and controls (p < 0.001 and p < 0.001, respectively). The number of mothers who indicated that they did not have enough information about asthma and treatment was also higher in the non-adherent group. PARI subtest scores were not different between the adherent and non-adherent groups. CONCLUSIONS In our study, it was found that mothers' anxiety levels and their knowledge about asthma and medications were associated with treatment adherence in children with asthma. Psychological and educational support to the families of children with asthma would improve their treatment adherence and efficacy.

中文翻译：

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母亲焦虑和态度对哮喘儿童吸入皮质类固醇依从性的影响。

目的 哮喘儿童长期使用吸入性皮质类固醇 (ICS) 会引起父母的严重担忧，从而导致治疗不依从性。本研究旨在调查母亲焦虑和态度对哮喘儿童 ICS 治疗依从性的影响。方法 患者组包括6-11岁的轻度至中度持续性哮喘儿童。将年龄相近的健康儿童作为对照组。根据ICS使用的规律性将患者组分为两类（治疗依从性和非依从性）。所有患者均使用儿童哮喘控制测试 (C-ACT) 进行评估，其母亲使用父母态度研究工具 (PARI) 和贝克焦虑量表 (BAI) 进行评估。结果 共有 156 名儿童（年龄：7.4 ± 1.4 岁，F/M：71/85）患有持续性哮喘和 60 名健康儿童（年龄：7.5 ± 1.3 岁，F/M：25/35）被纳入研究。哮喘患儿的依从率为52.6%。非依从性患者的母亲的 BAI 评分显着高于依从性患者和对照组（分别为 p < 0.001 和 p < 0.001）。在非依从组中，表示自己没有足够的哮喘和治疗信息的母亲数量也较高。PARI 分测验分数在依从组和非依从组之间没有差异。结论 在我们的研究中，发现母亲的焦虑水平及其对哮喘和药物的了解与哮喘患儿的治疗依从性相关。