BACKGROUND/OBJECTIVES Adverse reactions to local anesthetics are relatively common, but proven IgE-mediated allergy is extremely rare. We aimed to determine the frequency of local anesthetic allergy in pediatric patients. PATIENTS AND METHODS The medical records of 73 patients who presented to our clinic with a history of suspected allergic reaction to local anesthetics and underwent diagnostic testing between 2012 and 2020 were retrospectively analyzed. Diagnoses were based on case histories, skin tests, and subcutaneous challenge tests. RESULTS A total of 75 test series were carried out on the 73 patients (43 boys; median [IQR] age 9.25 [7.26-14.25] years, range 3-17.8 years). The most commonly tested drugs were lidocaine (n = 38; 50.6%) and prilocaine (n = 15; 20%). Local anesthetic allergy was confirmed in one (1.3%) of the 73 patients by positive subcutaneous challenge test with mepivacaine. CONCLUSION There are limited data in the current literature regarding local anesthetic allergies and diagnosis test results in pediatric patients. Proven local anesthetic allergy is less common than expected by society and physicians, and therefore diagnostic tests are needed for patients with no contra-indications such as severe or life-threatening reactions.

中文翻译：

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儿科患者的即时局部麻醉反应和诊断测试结果。

背景/目的 局部麻醉剂的不良反应相对常见，但经证实的 IgE 介导的过敏极为罕见。我们旨在确定儿科患者局部麻醉剂过敏的频率。患者与方法 回顾性分析了 2012 年至 2020 年间因疑似局部麻醉剂过敏史并接受诊断检测的 73 例患者的医疗记录。诊断基于病史、皮肤试验和皮下激发试验。结果共对 73 名患者（43 名男孩；中位 [IQR] 年龄 9.25 [7.26-14.25] 岁，范围 3-17.8 岁）进行了 75 个测试系列。最常测试的药物是利多卡因（n = 38；50.6%）和丙胺卡因（n = 15；20%）。1例（1. 73 名患者中的 3%) 用甲哌卡因皮下激发试验阳性。结论 目前文献中关于儿科患者局部麻醉剂过敏和诊断试验结果的数据有限。经证实的局部麻醉剂过敏并不像社会和医生预期的那么普遍，因此对于没有禁忌症（例如严重或危及生命的反应）的患者，需要进行诊断测试。